ncRNA name | Robo4 siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Macaca mulatta |
Tissues/Cell_line | rhesus choroid-retinal endothelial cell line RF/6A |
Methods | RT-PCR, qPCR, immunohistochemistry, Western blot, immunocytochemistry, siRNA transfection, MTT assay, Boyden chamber assay, immunocytochemistry, flow cytometry, tube formation assay |
Expression pattern | associated |
Functional description | Silencing the expression of Robo4 in RF/6A and RPE cells inhibited their proliferation and reduced their tolerance of hypoxic conditions. |
PubMed ID | 19495426 |
Year | 2009 |
Title | Expression of Robo4 in the fibrovascular membranes from patients with proliferative diabetic retinopathy and its role in RF/6A and RPE cells. |
Drug-related ncRNA | NO |
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